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"The 5 worst foods to eat if you have arthritis The #1 Worst Food to eat if you suffer from arthritis is sugar. Cookies, candy, ice cream, brownies, doughnuts ... all of these are loaded with sugar, levels of inflammation Worst Food #2: Nightshade Vegetables What's a nightshade vegetable? Nightshade vegetables include potatoes, tomatoes, eggplant, peppers and tobacco, all of these products contain trace amounts of alkaloids that can be harmful in heavy concentrations. Eating nightshade plants actually worsens arthritis because of the way they affect calcium metabolism in the body. These alkaloids may lead to calcium deposits in tendons, ligaments, cartilage and joints contributing to inflammation and joint pain. This effect can be worse for people who already have arthritis. Substances in nightshade plants can cause the worsening of an already existing inflammation. Worst Food #3: Blackened and Barbecued Foods Foods cooked at high temperatures often contain harmful by-products caused by the cooking process called Advanced Glycation End (AGEs). AGEs are highly inflammatory and can damage your joints and bones, making your arthritis worse. Worst Food #4: French Fries & Other Processed Fast Food French fries are by no means the only culprit soybean, corn, peanut, & sunflower oils are examples of vegetable oils that are rich in omega-6 fats, Too much Omega-6 causes inflammation. "